Xiaobing Zuo is a Physicist in X-Ray Science Division. He was born and grew up in Shandong, China. He obtained both his bachelor and master degrees from the University of Science and Technology of China (USTC). In 1998, he went to Northwestern University and joined Prof. Fred Lewis' lab as a Ph.D. student to study small molecule photochemistry and photophysics and charge transfer processes in DNA. After obtaining PhD degree, he joined Dr. Dave Tiede's lab at Chemistry Division of Argonne and measured the structures of DNAs, proteins, and nanostructures using SAXS and WAXS. From 2007 to 2010, he worked at Dr. Yun-Xing Wang’s lab at NIH to study RNA structures by combining SAXS and NMR spectroscopy techniques. Starting from Nov. 2010, he joined the Chemical and Materials Science group of X-ray Science Division. His expertise includes structural characterization of bioploymers and materials using x-ray scattering.

Sun, Y.; Zuo, X.; Sankaranarayanan, S. K.R. S.; Peng, P.; Narayanan, B.; Kamath, G., "Quantitative 3D evolution of colloidal nanoparticle oxidation in solution," Science, 2017, 356 (6335), 303-307.

Jiang. T., Vail, O.A.; Jiang, Z.; Zuo, X.; Conticello, V.P.; "Rational Design of Multilayer Collagen Nanosheets with Compositional and Structural Control," J. Am. Chem. Soc. 2015, 137 (24), 7793-7802 .

Zuo, X.; Wang, J.; Yu, P.; Eyler, D.; Xu, H.; Starich, M. R.; Tiede, D. M.; Simon, A. E.; Kasprzak, W.; Shapiro, B. A.; Schwieters, C. D.; Wang, Y. X.; The Ribosome Binding Structure Element in 3' UTR of Turnip Crinkle Virus RNA Folds into a tRNA-like Shape in Solution; Proc. Natl. Acad. Sci. USA, 2010, 107, 1385. [link]

Wang, J; Zuo, X. ; Yu, Y; Xu, H.; Starich, M. R.; Tiede, D. M.; Shapiro, B. A.; Schwieters, C. D.; Wang, X. Y.; A Method for Helical RNA Global Structure Determination in Solution Using Small-Angle X-Ray Scattering and NMR Measurements; J. Mol. Biol., 2009, 393, 717. [link]

Wang, J.; Zuo, X.; Yu, Y.; Byeon, I. L.; Jung, J.; Wang, X.; Dyba, M.; Seifert, S.; Schwieters, C. D.; Qin, J.; Gronenborn, A. M.; Wang, Y. X.; Determination of Multicomponent Protein Structures in Solution Using Global Orientation and Shape Restraints; J. Am. Chem. Soc., 2009, 131, 10507. [link]

Zuo, X.; Wang, J.; Foster, T. R.; Schwieters, C. D.; Tiede, D. M.; Butcher, S. E.; Wang, Y. X.; Global Molecular Structure and Interfaces: Refining an RNA:RNA Complex Structure Using Solution X-ray Scattering Data; J. Am. Chem. Soc., 2008, 130, 3292. [link]

O’Donnell, J. L.; Zuo, X.; Goshe, A. J.; Murthi, M.; Sariskov, L.; Snurr, R. Q.; Hupp, J. T.; Tiede, D. M.; Solution Phase Structural Analysis of Supramolecular Assemblies by High Angle Molecular Diffraction; J. Am. Chem. Soc., 2007, 129, 1578. [link]

Zuo, X.; Cui, G.; Merz, K. M.; Zhang, L.; Lewis, F. D.; Tiede, M. D.; X-ray Diffraction “Finger­printing” of DNA Structure in Solution for Quantitative Evaluation of Molecular Dynamics Simulation; Proc. Natl. Acad. Sci. USA, 2006, 103, 3534. [link]

Zuo, X.; Tiede, D. M.; Resolving Conflicting Crystallographic and NMR Models for Solution-State DNA with Molecular Solution X-ray Diffraction; J. Am. Chem. Soc., 2005, 127, 16. [link]

Lewis, F. D.; Zhang, L.; Zuo, X.; Orientation Control of Fluorescence Resonance Energy Transfer Using DNA as a Helical Scaffold; J. Am. Chem. Soc., 2005, 127, 10002. [link]

Lewis, F. D.; Liu, X.; Wu, Y.; Zuo, X.; Stepwise Evolution of the Structure and Electronic Properties of DNA; J. Am. Chem. Soc., 2003, 125, 12729. [link]

1. Synchrotron based x-ray techniques and data analysis methods for structures and dynamics of biopolymers, functional supramolecules and nanomaterials;

2. Time-resolved x-ray scattering for the biomolecular kinetic processes;

3. Structural methodology that combines x-ray scattering and other techniques such as NMR spectroscopy;

4. Structural biology and biophysics of functional RNA molecules.

1995. B.S. in Chemistry, Univeristy of Science and Technology of China, Hefei, China

1998. M.S. in Physical Chemistry, Univeristy of Science and Technology of China, Hefei, China

2002. Ph.D. in Phyiscal Organic Chemistry, Northwestern University, Evanston, IL USA

Physicist (7/2015 - present)
X-ray Science Division, Argonne National Laboratory, Argonne, IL

Assistant Physicist (11/2010 - 6/2015)
X-ray Science Division, Argonne National Laboratory, Argonne, IL

Cancer Research Training Award Fellow (3/2007-10/2010) 
Structural Biophysics Laboratory, National Cancer Institute, NIH, Frederick, MD

Postdoctoral Fellow (11/2002 - 12/2006)
Chemistry Division, Argonne National Laboratory, Argonne, IL

Ph.D. Student (02/1999 - 10/2002)
Chemistry Department, Northwestern University, Evanston, IL