The Advanced Photon Source
a U.S. Department of Energy Office of Science User Facility

Synchrotron-related Job Openings

To post a position, please submit job description, prerequisites, and contact information to Constance Vanni at Please note that postings are removed by request or one year after the original posting date.


Current Openings:

    Chemistry and Material Sciences Center for Advanced Radiation Sources (NSF’s ChemMatCARS), The University of Chicago



Posting Date


The Northeastern Collaborative Access Team (NE-CAT), located at the Advanced Photon Source at the Argonne National Laboratory in suburban Chicago, is seeking applicants for a beamline scientist position. The primary responsibilities of the staff scientist will be to provide user training and support using NE-CAT’s x-ray beamlines; assist in setting up experiments; provide crystallographic expertise to ensure the highest quality data and structures; and contribute to the continued development of software tools. Please click here for a full description of duties and responsibilities.

This is a 12-month benefits eligible full-time (100%FTE) appointment term which is renewable depending on funding and performance.
  commensurate with experience
Start:  August 1,2019

Interested candidates should submit a cover letter, curriculum vitae, copies of relevant publications, and contact information for three references electronically to Academic Jobs Online at Applications will be reviewed as they are received and will be accepted until the position is filled.  Please direct questions to Frank Murphy, NE-CAT Associate Director ( Cornell is an equal opportunity, affirmative action educator and employer.

July 9, 2019


The Industrial Macromolecular Crystallography Association - Collaborative Access Team (IMCA-CAT) and the Hauptman-Woodward Medical Research Institute (HWI) seek an inventive macromolecular crystallographer to join the IMCA-CAT team in accelerating pharmaceutical drug discovery through synchrotron-based structural biology research. As an employee of HWI, you will be based at the center of the team’s operations at the Advanced Photon Source (APS), Argonne National Laboratory, near Chicago, IL. This is an ideal position for a motivated scientist who is passionate about delivering strategic value, developing new technologies, and working in a high-powered, collaborative environment.

POSITION DESCRIPTION: This is an exciting time to join IMCA-CAT. Underway this summer is the first of a two-phase upgrade that will significantly increase throughput and establish a strong foundation upon which to build capacity. The second phase upgrade, currently in design, will profoundly increase capacity and dramatically expand capability for challenging research projects.

The successful candidate will be an integral part of these upgrade activities while maintaining flow of diffraction data for pharmaceutical research projects. The candidate will work closely with IMCA-CAT colleagues in an inclusive and respectful environment, and is expected to take initiative and contribute to the team effort.

TO APPLY: Send an introductory e-mail, CV, and contact information for three references to Lisa Keefe, IMCA-CAT Director and HWI Vice President of Advancing Therapeutics at

LEARN MORE: Visit our websites to learn more about IMCA-CAT ( and HWI (

June 27, 2019

BIOCARS, University of Chicago

BioCARS is a national user facility for synchrotron-based, dynamic studies in structural biology, located at Sector 14 of the Advanced Photon Source, at Argonne National Laboratory. BioCARS is an integral part of the multi-disciplinary Center for Advanced Radiation Sources (CARS) run by the University of Chicago. The mission of BioCARS is to provide state-of-the-art X-ray and laser facilities, scientific and technical expertise and support to enable national and international scientists to study the dynamic properties of biological systems by X-ray scattering techniques such as time-resolved diffraction and SAXS/WAXS. The overall goal of user experiments is to understand basic biological and biochemical processes in structural and dynamic terms, at the level of atomic resolution and on a time scale from 100 picoseconds to seconds. Scientific problems addressed by BioCARS are fundamental to highly relevant biomedical problems and of practical importance to both pharmaceutical and biotechnological industries.

1) Participate in the development and implementation of instrumentation and software for advanced experimental methods in the area of time-resolved X-ray diffraction and solution scattering.
2) Participate in beamline instrumentation maintenance, particularly with ns and ps laser systems, as well as software improvements and development.
3) Provide support and collaborate with users on experiment planning, design and implementation, and data processing and analysis.
4) Assist the BioCARS user community in using the BioCARS facilities.
5)  Participate in disseminating BioCARS accomplishments in peer reviewed and other publications, present findings at meetings, participate in workshops to train new scientific users.
6) BioCARS staff members support national and international scientists conducting experiments at the APS. This requires occasional evening and weekend support. 

For additional details, see here. Contact Vukica Srajer for further information.

May 24, 2019

Chemistry and Material Sciences Center for Advanced Radiation Sources (NSF’s ChemMatCARS), University of Chicago

Applications are invited for a post-doctoral scholar position with the University of  Chicago Center for Advanced Radiation Sources (CARS) to study heterogeneities at liquid surfaces and interfaces. Although synchrotron x-ray techniques have been used successfully to characterize homogeneous liquid surfaces and interfaces, the study of heterogeneities on the nanoscale requires new approaches which will be investigated in this position. This experimental program will utilize the ChemMatCARS liquid interface x-ray scattering facility at Sector 15 of the Advanced Photon Source (APS), Argonne National Laboratory (ANL). The successful applicant will also participate in supporting the general user program in liquid surface and interface scattering at ChemMatCARS. Applicants should have or be about to obtain a recent Ph.D. in experimental studies of soft or condensed matter physics, physical chemistry, or a closely related field. Prior experience with synchrotron x-ray scattering, strong experimental skills, scientific initiative, excellent communication skills, and the ability to work well with others are preferred. The ability to satisfy requirements to work at Argonne National Laboratory is required.

The anticipated duration of this position is two to three years, though extension beyond the first year will be by mutual consent. Review of applications will begin on March 15, 2019 and continue until the position is filled. Interested individuals should send a resume and arrange to have two letters of reference sent to Dr. Binhua Lin ( of the University of Chicago and Prof. Mark Schlossman ( of the University of Illinois at Chicago.

NSF’s ChemMatCARS, funded by the NSF and operated by the University of Chicago, is a national synchrotron facility at APS (ANL) to investigate dynamic and structural properties of interest to chemical, materials, and physical scientists (see The University of Chicago is an affirmative action/equal opportunity employer.

February 8, 2019


Employment opportunity notices will be posted upon request.

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Last updated: 7/10/2019