Advanced Photon Source User Activity Report
SBC-CAT, Structural Biology Center Collaborative Access Team


A unique zinc-binding site revealed by the high-resolution x-ray structure of homotrimeric Apo2L/TRAIL
S.G. Hymowitz, M.P. O'Connell, M.H. Ultsch, A. Hurst, K. Totpal, A. Ashkenazi, R.F. Kelley, and A.M. de Vos

Crystallographic evidence for Try157 functioning as the active site base in human UDP-galactose 4-epimerase
J.B. Thoden, T.M. Wohlers, J.L. Fridovich-Keil, and H.M. Holden

Crystallographic studies of Thermus aquaticus RNA polymerase
S.A. Darst, E.A. Campbell, and K. Murakami

Crystallographic studies on the ribosome, a large macromolecular assembly exhibiting severe nonisomorphism, extreme beam sensitivity, and no internal symmetry
A. Yonath, J. Harms, H.A. Hansen, A. Bashan, F. Schlunzen, I. Levin, I. Kolln, A. Tocilj, I. Agmon, M. Peretz, H. Bartels, W.S. Bennett, S. Krumbholz, D. Janell, S. Weinstein, T. Auerbach, H. Avila, M. Piolleti, S. Morlang, and F. Franceschi

Crystallography of ribosomes
A. Yonath

Crystal structure of isocitrate dehydrogenase from Bacillus subtilis
S.K. Singh, S.P. Miller, D.C. LaPorte, and L.J. Banaszak

Crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana
S. Suresh, S. Turley, F.R. Opperdoes, P.A.M. Michels, and W.G.J. Hol

Crystal structure of the catalytic portion of human HMG-CoA reductase
E.S. Istvan, M. Palnitkar, S.K. Buchanan, and J. Deisenhofer

Crystal structure of the E. coliYrdC protein
M. Egli, M. Teplova, V. Tereshko, R. Sanishvili, A. Joachimiak, and W.E. Anderson

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus
DNA polymerase I: structural basis for nucleotide incorporation
Y. Li, S. Korolev, and G. Waksman

Elucidating the medium-resolution structure of ribosomal particles:  an interplay between electron cryomicroscopy and x-ray crystallography
A. Yonath, J. Harms, A. Tocilj, I. Levin, I. Agmon, H. Stark, I. Kolln, M. van Heel, M. Cuff, F. Schlunzen, A. Bashan, and F. Franceschi

Functional universality and evolutionary diversity:  insights from the structure of the ribosome
A. Yonath and F. Franceschi

Lambda-6 light chain, Wil
P.R. Pokkuluri, A. Solomon, D.T. Weiss, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, M. Szpunar, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, X. Cai, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, X. Cai, M. Gu, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, R. Raffen, L. Dieckman, C. Boogard, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, X. Cai, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, X. Cai, G. Johnson, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, R. Raffen, F.J. Stevens, and M. Schiffer

MAD phasing on the SBC-CAT 19-ID undulator beamline at the APS
R. Sanishvili, G. Evans, M. Walsh, R. Zhang, R. Alkire, and A. Joachimiak

Mechanism of hyaluronan binding and degradation: structure of Streptococcus pneumoniae hyaluronate lyase in complex with hyaluronic acid disaccharide at 1.7 Å resolution
K. Ponnuraj and M.J. Jedrzejas

Metal compounds as tools for the construction and the interpretation of medium-resolution maps of ribosomal particles
A. Yonath, S. Weinstein, W. Jahn, C. Glotz, F. Schlunzen, I. Levin, D. Janell, J. Harms, I. Kolln, H.A. Hansen, M. Gluhmann, W.S. Bennett, H. Bartels, A. Bashan, I. Agmon, M. Kessler, M. Pioletti, H. Avila, K. Anagnostopoulos, M. Peretz, T. Auerbach, and F. Franceschi

Monomeric sarcosine oxidase: structure of a covalently flavinylated amine oxidizing enzyme
P. Trickey, M. Wagner, M.S. Jorns, and F.S. Mathews

N10-formyltetrahydrofolate synthetase
R. Radfar, W. Minor, and L. Lebioda

Probing covalent flavinylation in the flavocytochrome p-cresol methylhydroxylase
L.M. Cunane, Z.-W. Chen, F.S. Mathews, and W.S. McIntire

Rapid protein crystal structure determination using third-generation synchrotron sources
M.A. Walsh, I. Dementieva, G. Evans, R. Sanishvili, and A. Joachimiak

P.R. Pokkuluri, R. Raffen, F.J. Stevens, and M. Schiffer

Structural determinants for visual arrestin's specificity and basal state
C. Schubert, P.B. Sigler, and J.A. Hirsch

Structural determinants of preinitiation complex assembly on human Pol II promoters
F.T.F. Tsai and P.B. Sigler

Structural studies of a functional form of pneumolysin: a virulence factor from Streptococcus pneumoniae
S. Kelly and M.J. Jedrzejas

Structural studies of an ecotin variant
G. Pal, H. Christinger, A.A. Kossiakoff, and C. Wiesmann

Structural studies of a soluble monomeric quinohemoprotein alcohol dehydrogenases from Pseudomonas putida HK5
F.S. Mathews, Z.-w. Chen, K. Matsushita, T. Yamashita, H. Toyama, O. Adachi, and H.D. Bellamy

Structural studies of FceRI
C. Eigenbrot and J. Stamos

Structural studies of p185/HER2
F.F. Vajdos, H. Christinger, and A.M. de Vos

Structural studies of the recombinant flavin-binding domain of bakers yeast flavocytochrome b2
L.M. Cunane, J.D. Barton, Z.-w. Chen, F.S. Mathews, F.E. Welsh, S.K. Chapman, and G.A. Reid

Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution
Y.G. Gao, H. Robinson, R. Sanishvili, A. Joachimiak, and A.H. Wang

Structure of a manganese-containing homoprotocatechuate 2,3-dioxygenase from Arthrobacter globiformus CM-2 at 1.5 Å resolution
M. Vetting and D. Ohlendorf

Structure of homoprotocatechuate 2,3-dioxygenase from Brevibacterium fuscum at 1.6 Å resolution
M. Vetting and D. Ohlendorf

Structure of streptococcal pyrogenic exotoxin A
C. Earhart, G. Vath, M. Roggiani, P. Schlievert, and D. Ohlendorf

Structure studies of g-carboxymuconolactone decarboxylase from Acinetobacter sp. ADP1
M. Vetting and D. Ohlendorf

The small ribosomal subunit from Thermus thermophilusat 4.5 Å resolution:  pattern fittings and the identification of a functional site
A. Yonath, A. Tocilj, F. Schlunzen, D. Janell, M. Gluhmann, H.A. Hansen, J. Harms, A. Bashan, H. Bartels, I. Agmon, and F. Franceschi

The small subunit of carbamoyl phosphate synthetase:  snapshots along the reaction pathway
J.B. Thoden, X. Huang, F.M. Raushel, and H.M. Holden

The structural basis for the oriented assembly of a TBP/TFB/promoter complex
O. Littlefield, Y. Korkhin, and P. Sigler

The Structural Biology Center at the Advanced Photon Source
G. Rosenbaum, R. Alkire, N.C. Duke, S.L. Ginell, F. Rotella, R. Sanishvilli, R. Zhang, and A. Joachimiak

The structure of the ligand-binding domain of neurexin 1b: regulation of LNS domain function by alternative splicing
G. Rudenko, T. Nguyen, Y. Chelliah, T.C. Sudhof, and J. Deisenhofer

The three-dimensional structure of Escherichia coliasparagine synthetase B:  a short journey from substrate to product
T.M. Larsen, S.K. Boehlein, S.M. Schuster, N.G.J. Richards, J.B. Thoden, H.M. Holden, and I. Rayment

Thymidylate synthase
J. Phan, W. Minor, and L. Lebioda

Time-efficient data collection on crystals of the large ribosomal subunit from Haloarcula marimortui
P. Nissen, N. Ban, J. Hansen, P.B. Moore, and T.A. Steitz

Ultrahigh-resolution diffraction from the 'blue' copper protein anicyanin
C.J. Carrell, Z.-W. Chen, L.M. Cunane, P. Trickey, and F.S. Mathews

X-ray crystallography of bovine rhodopsin
T. Okada, I. Le Trong, C.A. Behnke, B.A. Fox, D.C. Teller, R.E. Stenkamp, and K. Palczewski

X-ray crystal structure of peptide-bound GroEL
L. Chen and P.B. Sigler

X-ray studies of recombinant rat kidney long-chain hydroxy acid oxidase
L.M. Cunane, J.D. Barton, Z.-w. Chen, F.S. Mathews, A. Belmouden, K.H.D. Lê, and F. Lederer